Oxymetholone is a potent oral anabolic steroid developed in the 1960s and originally used for the treatment of anemia, osteoporosis, and muscle wasting conditions. It is a derivative of dihydrotestosterone (DHT) and exhibits a strong anabolic effect with relatively moderate androgenic activity. In performance settings, it is valued for rapid muscle mass gain, increased strength, and enhanced red blood cell production. Although it does not aromatize into estrogen, it can still produce estrogen-like effects such as water retention and gynecomastia. Due to its 17α-alkylated structure, it is orally active but may exert stress on the liver with prolonged use. Main Effects Rapid and significant increase in muscle mass; Strong enhancement of strength and power output; Stimulation of red blood cell production and oxygen delivery; ускоряет восстановление и регенерацию тканей; Promotes joint comfort through mild water retention; Improves overall endurance and physical performance Precautions Hepatotoxic due to 17α-alkylation; Monitor liver enzymes, blood pressure, and lipid profile; Avoid prolonged use or high dosages; Post-cycle therapy (PCT) is required after discontinuation Side Effects Water retention and bloating; Increased blood pressure; Suppression of natural testosterone production; Gynecomastia despite lack of aromatization; Liver strain or elevated enzymes; Acne, oily skin, mood fluctuations Contraindications Liver or kidney disease; Prostate or breast carcinoma; Pregnancy and breastfeeding; Hypersensitivity to anabolic steroids; Hypercalcemia Storage Store at 20–25 °C (68–77 °F); Protect from light and moisture; Do not refrigerate or freeze; Keep out of reach of children Mechanism of Action Oxymetholone binds to androgen receptors in muscle tissue, stimulating protein synthesis and nitrogen retention, which leads to rapid increases in muscle size and strength. It also enhances erythropoiesis, improving oxygen transport and endurance. Pharmacological Profile Half-life: approximately 8–10 hours; Strong anabolic effect with moderate androgenic activity; Does not aromatize but may exhibit estrogen-like side effects; Reduces SHBG levels, increasing free testosterone; High oral bioavailability with notable hepatic impact