Name: Tirzepatide Pen
Brand: Hilma Biocare
SKU: 08de9c5f-6bc2-456c-832e-2b4acd4d2fe7
Price: 80.00 EUR
Availability: LimitedAvailability

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Concentration

info

Tirzepatide Pen 10 mg
Product Description

Tirzepatide is a dual agonist of GIP and GLP-1 receptors, designed to support glucose regulation and weight management. It is an analogue of gastric inhibitory polypeptide (GIP), a natural human hormone that stimulates insulin secretion from the pancreas.

The molecule is a linear polypeptide consisting of 39 amino acids and is chemically modified through lipidation, which enhances its cellular absorption and metabolic stability, allowing for prolonged therapeutic action.

Indications
Tirzepatide is indicated for the treatment of type 2 diabetes mellitus and for weight reduction. It is used to improve glycemic control in combination with a balanced diet and regular physical activity.

Mechanism of Action
Tirzepatide acts as a dual incretin receptor agonist, targeting both GIP and GLP-1 pathways.

It has a higher affinity for GIP receptors compared to GLP-1 receptors, which contributes to a more significant reduction in blood glucose levels compared to traditional GLP-1 receptor agonists. By mimicking the natural action of GIP, it enhances insulin secretion in a glucose-dependent manner.

At the GLP-1 receptor level, tirzepatide promotes the formation of cyclic AMP (cAMP), a key intracellular messenger involved in regulating glucose, glycogen, and lipid metabolism. Unlike some other agents, it shows a signaling preference that avoids excessive beta-arrestin recruitment.

This combined activity results in increased insulin secretion and improved metabolic regulation. Additionally, tirzepatide elevates levels of adiponectin and adipokines, which play an important role in glucose and lipid metabolism. Clinical data show an increase of up to 26% from baseline after 26 weeks of treatment at a 10 mg dose.

Buy Tirzepatide Pen 10 mg Hilma Biocare online. Advanced dual GIP & GLP-1 for weight loss, appetite control, blood sugar balance, and metabolic support.